To be, or not to be: Conserved eukaryotic regulatory networks?

Metabolic processes, signal transduction, gene regulation, gene and protein expression in biological systems, all are controlled by means of networks. Several bioinformatics approaches have been introduced to infer networks from high-throughput data. But still, most networks are not known in detail for most biological systems. Thus, the question arises whether biological networks can be transferred between species, or whether they are specific for individual contexts: to be, or not to be.