Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions

Mariangela Agamennone; Alessandro Nicoli; Sebastian Bayer; Verena Weber; Luca Borro; Shailendra Gupta; Marialuigia Fantacuzzi; Antonella Di Pizio

doi:10.1016/bs.mcb.2021.06.012

Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions

Mariangela Agamennone (First Author)
, Alessandro Nicoli (Co-Author)
, Sebastian Bayer (Co-Author)
, Verena Weber (Co-Author)
, Luca Borro (Co-Author)
, Shailendra Gupta (Co-Author)
, Marialuigia Fantacuzzi (Co-Author)
, Antonella Di Pizio^* (Last Author)

^*Corresponding author for this work

Molecular Modeling

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

3 Scopus citations

Abstract

Protein-protein interactions (PPIs) play a key role in many biological processes and are intriguing targets for drug discovery campaigns. Advancements in experimental and computational techniques are leading to a growth of data accessibility, and, with it, an increased need for the analysis of PPIs. In this respect, visualization tools are essential instruments to represent and analyze biomolecular interactions. In this chapter, we reviewed some of the available tools, highlighting their features, and describing their functions with practical information on their usage.

Original language	English
Title of host publication	Biomolecular Interactions Part A
Editors	Arun K. Shukla
Publisher	Academic Press Inc.
Pages	271-307
Number of pages	37
ISBN (Print)	9780128233511
DOIs	https://doi.org/10.1016/bs.mcb.2021.06.012
State	Published - Jan 2021

Publication series

Name	Methods in Cell Biology
Volume	166
ISSN (Print)	0091-679X

Keywords

3D representation
Molecular interactions
Protein
Protein interface
Protein photorealism
Protein-protein interactions
Surface

Access to Document

10.1016/bs.mcb.2021.06.012

Cite this

Agamennone, M., Nicoli, A., Bayer, S., Weber, V., Borro, L., Gupta, S., Fantacuzzi, M., & Di Pizio, A. (2021). Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions. In A. K. Shukla (Ed.), Biomolecular Interactions Part A (pp. 271-307). (Methods in Cell Biology; Vol. 166). Academic Press Inc.. https://doi.org/10.1016/bs.mcb.2021.06.012

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title = "Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions",

abstract = "Protein-protein interactions (PPIs) play a key role in many biological processes and are intriguing targets for drug discovery campaigns. Advancements in experimental and computational techniques are leading to a growth of data accessibility, and, with it, an increased need for the analysis of PPIs. In this respect, visualization tools are essential instruments to represent and analyze biomolecular interactions. In this chapter, we reviewed some of the available tools, highlighting their features, and describing their functions with practical information on their usage.",

keywords = "3D representation, Molecular interactions, Protein, Protein interface, Protein photorealism, Protein-protein interactions, Surface",

author = "Mariangela Agamennone and Alessandro Nicoli and Sebastian Bayer and Verena Weber and Luca Borro and Shailendra Gupta and Marialuigia Fantacuzzi and \{Di Pizio\}, Antonella",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

month = jan,

doi = "10.1016/bs.mcb.2021.06.012",

language = "English",

isbn = "9780128233511",

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publisher = "Academic Press Inc.",

pages = "271--307",

editor = "Shukla, \{Arun K.\}",

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}

Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions. / Agamennone, Mariangela (First Author); Nicoli, Alessandro (Co-Author); Bayer, Sebastian (Co-Author) et al.
Biomolecular Interactions Part A. ed. / Arun K. Shukla. Academic Press Inc., 2021. p. 271-307 (Methods in Cell Biology; Vol. 166).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Protein-protein interactions at a glance

T2 - Protocols for the visualization of biomolecular interactions

AU - Agamennone, Mariangela

AU - Nicoli, Alessandro

AU - Bayer, Sebastian

AU - Weber, Verena

AU - Borro, Luca

AU - Gupta, Shailendra

AU - Fantacuzzi, Marialuigia

AU - Di Pizio, Antonella

PY - 2021/1

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N2 - Protein-protein interactions (PPIs) play a key role in many biological processes and are intriguing targets for drug discovery campaigns. Advancements in experimental and computational techniques are leading to a growth of data accessibility, and, with it, an increased need for the analysis of PPIs. In this respect, visualization tools are essential instruments to represent and analyze biomolecular interactions. In this chapter, we reviewed some of the available tools, highlighting their features, and describing their functions with practical information on their usage.

AB - Protein-protein interactions (PPIs) play a key role in many biological processes and are intriguing targets for drug discovery campaigns. Advancements in experimental and computational techniques are leading to a growth of data accessibility, and, with it, an increased need for the analysis of PPIs. In this respect, visualization tools are essential instruments to represent and analyze biomolecular interactions. In this chapter, we reviewed some of the available tools, highlighting their features, and describing their functions with practical information on their usage.

KW - 3D representation

KW - Molecular interactions

KW - Protein

KW - Protein interface

KW - Protein photorealism

KW - Protein-protein interactions

KW - Surface

UR - https://www.scopus.com/pages/publications/85111616224

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DO - 10.1016/bs.mcb.2021.06.012

M3 - Chapter

C2 - 34752337

AN - SCOPUS:85111616224

SN - 9780128233511

T3 - Methods in Cell Biology

SP - 271

EP - 307

BT - Biomolecular Interactions Part A

A2 - Shukla, Arun K.

PB - Academic Press Inc.

ER -

Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions

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Verena Weber

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Protein-protein interactions at a glance: Protocols for the visualization of biomolecular interactions

Abstract

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Verena Weber

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