PLMaddon: A power-law module for the Matlab™ SBToolbox

Julio Vera; Cheng Sun; Yvonne Oertel; Olaf Wolkenhauer

doi:10.1093/bioinformatics/btm245

PLMaddon: A power-law module for the Matlab™ SBToolbox

Julio Vera^*, Cheng Sun, Yvonne Oertel, Olaf Wolkenhauer

^*Corresponding author for this work

University of Rostock

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Summary: PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab ™ toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-law's logarithmic gains and sensitivities.

Original language	English
Pages (from-to)	2638-2640
Number of pages	3
Journal	Bioinformatics
Volume	23
Issue number	19
DOIs	https://doi.org/10.1093/bioinformatics/btm245
State	Published - 1 Oct 2007
Externally published	Yes

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10.1093/bioinformatics/btm245

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abstract = "Summary: PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab {\texttrademark} toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-law's logarithmic gains and sensitivities.",

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AU - Wolkenhauer, Olaf

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N2 - Summary: PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab ™ toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-law's logarithmic gains and sensitivities.

AB - Summary: PLMaddon is a General Public License (GPL) software module designed to expand the current version of the SBToolbox (a Matlab ™ toolbox for systems biology; www.sbtoolbox.org) with a set of functions for the analysis of power-law models, a specific class of kinetic models, set in ordinary differential equations (ODE) and in which the kinetic orders can have positive/negative non-integer values. The module includes functions to generate power-law Taylor expansions of other ODE models (e.g. Michaelis-Menten type models), as well as algorithms to estimate steady-states. The robustness and sensitivity of the models can also be analysed and visualized by computing the power-law's logarithmic gains and sensitivities.

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JO - Bioinformatics

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PLMaddon: A power-law module for the Matlab™ SBToolbox

Abstract

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