Labeling studies on the formation pathway of Nε- carboxymethyllysine in Maillard-type reactions

Martina Kasper; Peter Schieberle

doi:10.1196/annals.1333.007

Labeling studies on the formation pathway of N^ε- carboxymethyllysine in Maillard-type reactions

Martina Kasper
, Peter Schieberle^*

^*Corresponding author for this work

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

N^ε-carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon-13 in different positions, a new pathway is proposed for CML formation without involving free glyoxal or autoxidation reactions.

Original language	English
Pages (from-to)	59-62
Number of pages	4
Journal	Annals of the New York Academy of Sciences
Volume	1043
DOIs	https://doi.org/10.1196/annals.1333.007
State	Published - 2005
Externally published	Yes

Keywords

Advanced glycation end products (AGEs)
N-carboxymethyllysine (CML)

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10.1196/annals.1333.007

Cite this

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title = "Labeling studies on the formation pathway of Nε- carboxymethyllysine in Maillard-type reactions",

abstract = "Nε-carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon-13 in different positions, a new pathway is proposed for CML formation without involving free glyoxal or autoxidation reactions.",

keywords = "Advanced glycation end products (AGEs), N-carboxymethyllysine (CML)",

author = "Martina Kasper and Peter Schieberle",

year = "2005",

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journal = "Annals of the New York Academy of Sciences",

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AU - Kasper, Martina

AU - Schieberle, Peter

PY - 2005

Y1 - 2005

N2 - Nε-carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon-13 in different positions, a new pathway is proposed for CML formation without involving free glyoxal or autoxidation reactions.

AB - Nε-carboxymethyllysine (CML) is among the most often studied advanced glycation end products (AGEs) in foods and medicine, and several pathways have been suggested for its formation. Based on the results of model studies using glucose labeled with carbon-13 in different positions, a new pathway is proposed for CML formation without involving free glyoxal or autoxidation reactions.

KW - Advanced glycation end products (AGEs)

KW - N-carboxymethyllysine (CML)

UR - https://www.scopus.com/pages/publications/23744457477

U2 - 10.1196/annals.1333.007

DO - 10.1196/annals.1333.007

M3 - Article

C2 - 16037222

AN - SCOPUS:23744457477

SN - 0077-8923

VL - 1043

SP - 59

EP - 62

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

ER -

Labeling studies on the formation pathway of N^ε- carboxymethyllysine in Maillard-type reactions

Abstract

Keywords

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