Dark coffee consumption protects human blood cells from spontaneous DNA damage

Gudrun Pahlke (First Author), Eva Attakpah (Co-Author), Georg Aichinger (Co-Author), Katarina Ahlberg (Co-Author), Christina Maria Hochkogler (Co-Author), Kerstin Schweiger (Co-Author), Dorothea Schipp (Co-Author), Veronika Somoza (Co-Author), Doris Marko* (Last Author)

*Corresponding author for this work

Research output: Contribution to journalComment/debate

10 Scopus citations

Abstract

In the original article, there is an error. The number of non-compliant participants, mentioned in section 2. Materials and methods, subsection 2.7 Statistical analysis, PP population is indicated as 10 and the number of participants showing higher levels of NMP/creatinine levels with 8. These two numbers are wrong and in contradiction to Hochkogler et al. (2019, Journal of Functional Foods, doi: https://doi.org/10.1016/j.jff.2019.02.009) who describe the same intervention study in detail. The correct number of non-compliant participants of the intervention study is 9 instead, and 7 participants showed higher NMP/ creatinine levels according to Hochkogler et al. (2019, Journal of Functional Foods, doi: https://doi.org/10.1016/j.jff.2019.02.009). For better understanding of the population used for statistics following sentence should be modified: ITT population consisted of 96 volunteers, 23 men and 25 women allocated to each of the treatment groups (control and coffee). Modification: “ITT population started with 96 volunteers, 23 men and 25 women allocated to each of the treatment groups (control and coffee). A correction (marked in bold) is asked to be made to Materials and methods, subsection 2.7 Statistical analysis, ITT population as follows: ITT population started with 96 volunteers, 23 men and 25 women allocated to each of the treatment groups (control and coffee). One volunteer of the test group dropped out in the course of intervention. Missing measurements for Visit 2 were replaced by carrying forward the observed values at Visit 1. PP population as follows: In 9 samples signs of non-compliance were detected in urine samples (Hochkogler et al., 2019), for 7 participants showing higher NMP/creatinine concentration than it should be expected under abstention from coffee consumption (i.e. >0.2 nmol/μmol, (Lang, Wahl, Stark, & Hofmann, 2011). The author apologizes for any inconvenience this may have caused.

Original languageEnglish
Article number103989
Pages (from-to)285–295
Number of pages11
JournalJournal of Functional Foods
Volume71
DOIs
StatePublished - Aug 2020
Externally publishedYes

Keywords

  • Coffee
  • DNA integrity
  • human PBLs
  • Keap1
  • Nrf2

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