TY - GEN
T1 - Bitter taste receptors and their cells
AU - Behrens, Maik
AU - Reichling, Claudia
AU - Batram, Claudia
AU - Brockhoff, Anne
AU - Meyerhof, Wolfgang
PY - 2009/7
Y1 - 2009/7
N2 - The molecular basis of human bitter taste perception is an area of intense research. Only 25 G protein-coupled receptors belonging to the hTAS2R gene family face the challenge to detect thousands of structurally different bitter compounds, most of which are plant metabolites. Since many natural bitter compounds are highly toxic, whereas others are part of our daily diets, bitter taste was crucial during evolution and still most likely affects our food selection. The article presented here addresses biosynthesis, functional analyses of TAS2Rs and TAS2R variants, as well as gustatory expression of hTAS2R genes.
AB - The molecular basis of human bitter taste perception is an area of intense research. Only 25 G protein-coupled receptors belonging to the hTAS2R gene family face the challenge to detect thousands of structurally different bitter compounds, most of which are plant metabolites. Since many natural bitter compounds are highly toxic, whereas others are part of our daily diets, bitter taste was crucial during evolution and still most likely affects our food selection. The article presented here addresses biosynthesis, functional analyses of TAS2Rs and TAS2R variants, as well as gustatory expression of hTAS2R genes.
KW - Bitter taste receptor
KW - G protein-coupled receptors
KW - TAS2R
UR - https://www.scopus.com/pages/publications/68649098772
U2 - 10.1111/j.1749-6632.2009.03897.x
DO - 10.1111/j.1749-6632.2009.03897.x
M3 - Conference contribution
C2 - 19686120
AN - SCOPUS:68649098772
SN - 9781573317382
T3 - Annals of the New York Academy of Sciences
SP - 111
EP - 115
BT - International Symposium on Olfaction and Taste
PB - Blackwell Publishing Inc.
ER -