Agent-based simulation of molecular processes: An application to actin-polymerisation

Stefan Pauleweit*, J. Barbara Nebe, Olaf Wolkenhauer

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Agent-based modelling is widely used in ecology, economics and the social sciences. For the life science it is an increasingly used technology. Here we use agent-based modelling to simulate the formation of actin filaments, which is a major part in the cytoskeleton of the cell and plays a role in a number of cell functions. We present in this paper three models with different levels of detail and show the potential of agent-based models in systems biology by comparing the simulations to already published results.

Original languageEnglish
Title of host publicationSIMULTECH 2011 - Proceedings of 1st International Conference on Simulation and Modeling Methodologies, Technologies and Applications
Pages276-282
Number of pages7
StatePublished - 2011
Externally publishedYes
Event1st International Conference on Simulation and Modeling Methodologies, Technologies and Applications, SIMULTECH 2011 - Noordwijkerhout, Netherlands
Duration: 29 Jul 201131 Jul 2011

Publication series

NameSIMULTECH 2011 - Proceedings of 1st International Conference on Simulation and Modeling Methodologies, Technologies and Applications

Conference

Conference1st International Conference on Simulation and Modeling Methodologies, Technologies and Applications, SIMULTECH 2011
Country/TerritoryNetherlands
CityNoordwijkerhout
Period29/07/1131/07/11

Keywords

  • Actin polymerisation
  • Agent-based model
  • Arp2/3
  • Systems biology

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