A new phytoecdysteroid from the stem bark of Vitex cienkowskii

Timo D. Stark; Julius Rami; Sonja Fröhlich; Patrick Weiss; Wolfgang Vierling; Alain B. Dongmo; Thomas Hofmann

doi:10.1007/s00217-020-03591-z

A new phytoecdysteroid from the stem bark of Vitex cienkowskii

Timo D. Stark^*, Julius Rami, Sonja Fröhlich, Patrick Weiss, Wolfgang Vierling, Alain B. Dongmo, Thomas Hofmann

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

To investigate differences in the metabolome of the stem bark of Vitex cienkowskii harvested at three different locations and three different seasons, their extracts were analyzed by means of UPLC–ESI–IMS–TOF MS^e. One marker metabolite was isolated and chemically characterized, which was identified as the new compound 20,24-dihydroxy,24-hydroxymethylecdysone (1). IMS showed two drift time species for 1 which could be used as new and additional characteristic compound parameters in compound identification to reduce dereplication and false positives.

Original language	English
Pages (from-to)	2485-2491
Number of pages	7
Journal	European Food Research and Technology
Volume	246
Issue number	12
DOIs	https://doi.org/10.1007/s00217-020-03591-z
State	Published - Dec 2020
Externally published	Yes

Keywords

20,24-Dihydroxy,24-hydroxymethylecdysone
CCS
Conformers
Ion mobility
Non-targeted UPLC–ESI–IMS–TOF–MS profiling

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title = "A new phytoecdysteroid from the stem bark of Vitex cienkowskii",

abstract = "To investigate differences in the metabolome of the stem bark of Vitex cienkowskii harvested at three different locations and three different seasons, their extracts were analyzed by means of UPLC–ESI–IMS–TOF MSe. One marker metabolite was isolated and chemically characterized, which was identified as the new compound 20,24-dihydroxy,24-hydroxymethylecdysone (1). IMS showed two drift time species for 1 which could be used as new and additional characteristic compound parameters in compound identification to reduce dereplication and false positives.",

keywords = "20,24-Dihydroxy,24-hydroxymethylecdysone, CCS, Conformers, Ion mobility, Non-targeted UPLC–ESI–IMS–TOF–MS profiling",

author = "Stark, \{Timo D.\} and Julius Rami and Sonja Fr{\"o}hlich and Patrick Weiss and Wolfgang Vierling and Dongmo, \{Alain B.\} and Thomas Hofmann",

note = "Publisher Copyright: {\textcopyright} 2020, The Author(s).",

year = "2020",

month = dec,

doi = "10.1007/s00217-020-03591-z",

language = "English",

volume = "246",

pages = "2485--2491",

journal = "European Food Research and Technology",

issn = "1438-2377",

number = "12",

}

TY - JOUR

T1 - A new phytoecdysteroid from the stem bark of Vitex cienkowskii

AU - Stark, Timo D.

AU - Rami, Julius

AU - Fröhlich, Sonja

AU - Weiss, Patrick

AU - Vierling, Wolfgang

AU - Dongmo, Alain B.

AU - Hofmann, Thomas

PY - 2020/12

Y1 - 2020/12

N2 - To investigate differences in the metabolome of the stem bark of Vitex cienkowskii harvested at three different locations and three different seasons, their extracts were analyzed by means of UPLC–ESI–IMS–TOF MSe. One marker metabolite was isolated and chemically characterized, which was identified as the new compound 20,24-dihydroxy,24-hydroxymethylecdysone (1). IMS showed two drift time species for 1 which could be used as new and additional characteristic compound parameters in compound identification to reduce dereplication and false positives.

AB - To investigate differences in the metabolome of the stem bark of Vitex cienkowskii harvested at three different locations and three different seasons, their extracts were analyzed by means of UPLC–ESI–IMS–TOF MSe. One marker metabolite was isolated and chemically characterized, which was identified as the new compound 20,24-dihydroxy,24-hydroxymethylecdysone (1). IMS showed two drift time species for 1 which could be used as new and additional characteristic compound parameters in compound identification to reduce dereplication and false positives.

KW - 20,24-Dihydroxy,24-hydroxymethylecdysone

KW - CCS

KW - Conformers

KW - Ion mobility

KW - Non-targeted UPLC–ESI–IMS–TOF–MS profiling

UR - https://www.scopus.com/pages/publications/85089660296

U2 - 10.1007/s00217-020-03591-z

DO - 10.1007/s00217-020-03591-z

M3 - Article

AN - SCOPUS:85089660296

SN - 1438-2377

VL - 246

SP - 2485

EP - 2491

JO - European Food Research and Technology

JF - European Food Research and Technology

IS - 12

ER -

A new phytoecdysteroid from the stem bark of Vitex cienkowskii

Abstract

Keywords

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